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Product Name | WWL70 |
Description | A selective inhibitor of ABHD6 (IC50 = 70 nM); increases Ucp1 expression and the OCR in differentiated 3T3-L1 mouse adipocytes at 10 µM; increases the expression of Ucp1, Prdm16, Tmem26, and Tbx1 in visceral adipose tissue in mice fed a high-fat diet at 10 mg/kg per day; reduces adipose tissue mass and prevents glucose-intolerance and increases in body weight in mice fed a high-fat diet; increases brain levels of 2-AG and decreases EAE severity in wild-type, but not CB2 receptor knockout, mice at 10 mg/kg per day starting at disease onset |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | WWL-70 ABHD-6 Ucp-1 3T3L1 PPAR-α GW6471 Prdm-16 Tmem-26 Tbx-1 triacyl-glycerol 2AG |
Gene, Accession, CAS # | CAS: 947669-91-2 |
Catalog # | 10011213-5 |
Price | $133.00 |
Order / More Info | WWL70 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |