ARRY-520 from CAYMAN CHEMICAL COMPANY
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| Product Name | ARRY-520 |
| Description | A potent Eg5 inhibitor (IC50 = 6 nM); selective for Eg5 over a panel of 8 kinesins (IC50s = >100 µM) and a panel of 224 kinases at 10 µM; induces time-and dose-dependent cell death in HL-60, Jurkat, OCI-AML3, U937, and MOLM-13 leukemic cells; induces cell cycle arrest at the G2/M phase in a p53- and XIAP-independent manner in OCI-AML3 cells; inhibits blast colony formation of bone marrow samples derived from human AML patients; completely eliminates tumors in the RPMI-8226 multiple myeloma and HL-60 and MV4-11 AML mouse xenograft models at 20 mg/kg per day , |
| Size | 10 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | Filanesib |
| Gene, Accession, CAS # | CAS: 885060-09-3 |
| Catalog # | 21883-10 |
| Price | $169.00 |
| Order / More Info | ARRY-520 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY