Kirenol from CAYMAN CHEMICAL COMPANY

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Product NameKirenol
DescriptionA diterpenoid with diverse biological activities; inhibits Gram-positive and Gram-negative bacterial growth in disc diffusion assays (MICs = 39-156 and 312.5-625 µg/ml, respectively); reduces K652 cell viability (IC50 = 18.19 µg/ml); reduces motor deficit, delays disease onset, and downregulates inflammatory CD4+IFN-γ+ Th1 cells and CD4+IL-17A+ Th7 cells in a mouse model of EAE at 2 mg/kg; reduces the arthritis index, NF-kB activity, and paw swelling and increases annexin-1 expression in a rat model of collagen-induced arthritis from 1-4 mg/kg; topical administration reduces edema induced carrageenan, CFA, and formalin in rats at 0.3-0.5% w/w
Size5 mg
Concentrationn/a
Applicationsn/a
Other NamesK-652 CD4 IL17A NFkB antiarthritic antiinflammatory GR-α IFNγ CD-4 Th-1 7 Sigesbeckia Siegesbeckia
Gene, Accession, CAS #CAS: 52659-56-0
Catalog #26212-5
Price$62.00
Order / More InfoKirenol from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com

http://www.caymanchem.com

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