MDL 800 from CAYMAN CHEMICAL COMPANY
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| Product Name | MDL 800 |
| Description | An allosteric SIRT6 activator; selectively activates SIRT6 deacetylase activity over SIRT1-5 and -7 and HDAC1-11 deacetylase activity in cell-free assays at 100 µM; induces histone deacetylation (IC50 = 23.3 µM) in and reduces proliferation of BEL-7405 HCC cells (EC50 = 90.4 µM); inhibits OGD-induced TNF-α release in primary mouse microglia from 0.1-5 µM; reduces tumor weight and volume in a BEL-7405 HCC mouse xenograft model at 50, 100, and 150 mg/kg |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | MDL800 SIRT-1 2 3 4 6 SIRT2 SIRT3 SIRT4 SIRT5 SIRT7 HDAC-1 2 HDAC11 BEL7405 TNFα |
| Gene, Accession, CAS # | CAS: 2275619-53-7 |
| Catalog # | 35528-5 |
| Price | $50.00 |
| Order / More Info | MDL 800 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY