NS 2028 from CAYMAN CHEMICAL COMPANY
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| Product Name | NS 2028 |
| Description | NS 2028 is a specific inhibitor of soluble guanylyl cyclase. It inhibits purified bovine lung guanylyl cyclase in a concentration dependent and irreversible manner with IC50 values of 30 and 200 nM for basal and NO-stimulated enzymes, respectively.{6642} S-nitroso-glutathione-enhanced guanylyl cyclase activity in mouse cerebellum homogenates is inhibited by NS 2028 with an IC50 value of 17 nM, making it about 4.7 fold more potent than ODQ, which has an IC50 value of 80 nM for inhibition of soluble guanylyl cyclase in the same assay.{6642} NS 2028 does not inhibit particulate guanylyl cyclase or adenylyl cyclase. |
| Size | 25 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | specificity inhibitors guanylyl cyclase NS2028 guanylate cyclic cGMP inhibits |
| Gene, Accession, CAS # | CAS: 204326-43-2 |
| Catalog # | 81600-25 |
| Price | $788.00 |
| Order / More Info | NS 2028 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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