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Product Name | CU-115 |
Description | A TLR8 antagonist (IC50 = 1.04 µM); selective for TLR8 over TLR7 (IC50 = >50 µM); inhibits increases in type I IFN transcriptional activity induced by 3p-hpRNA or G3-YSD in a luciferase reporter assay at 5 and 20 µM; decreases R-848-induced TNF-α and IL-1β production in THP-1 cells at 5 µM |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | CU115 TLR 7 8 ss RNA 3phpRNA G3YSD TNFα IL1β R848 THP1 |
Gene, Accession, CAS # | CAS: 2471982-20-2 |
Catalog # | 29815-1 |
Price | $117.00 |
Order / More Info | CU-115 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |