TCN 238 from CAYMAN CHEMICAL COMPANY
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| Product Name | TCN 238 |
| Description | An orally bioavailable positive allosteric modulator of mGluR4 (EC50 = 1 µM); has a greater than 30-fold selectivity for mGluR4 over mGluR5 in vitro; has no activity at concentrations up to 10 µM at A2A, 5-HT1A, or α2A-adrenergic receptors; reduces catalepsy in a haloperidol-induced catalepsy rat model of Parkinson's disease (ED50 = ~1 mg/kg); leads to downregulation of GRM4 and GABRA1 in rat brain without affecting hippocampal-dependent memory |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | TCN238 human rat motor dysfunction |
| Gene, Accession, CAS # | CAS: 125404-04-8 |
| Catalog # | 11994-5 |
| Price | $97.00 |
| Order / More Info | TCN 238 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
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