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Product Name | Cariprazine |
Description | An atypical antipsychotic; binds to dopamine D2L, D2S, and D3, 5-HT1A, 5-HT2A, 5-HT2B, histamine H1, and σ1 receptors (Kis = 0.085-23.44 nM); an antagonist of dopamine D2 and D3 receptors (Kbs = 0.759 and 0.316 nM, respectively); a partial agonist at dopamine D2 and D3 receptors; stimulates inositol phosphate production in murine A9 cells expressing human D2L receptors (EC50 = 3.16 nM); inhibits forskolin-induced cAMP accumulation in CHO cells expressing human D3 receptors (EC50 = 2.63 nM); inhibits amphetamine-induced hyperactivity and the conditioned avoidance response in rats (ED50s = 0.12 and 0.84 mg/kg, respectively); inhibits scopolamine-induced learning deficits in a water labyrinth learning test in rats from 0.02-0.08 mg/kg |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | RGH-188 |
Gene, Accession, CAS # | CAS: 839712-12-8 |
Catalog # | 31446-25 |
Price | $533.00 |
Order / More Info | Cariprazine from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |