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Product Name | Caerulomycin A |
Description | A fungal metabolite with antifungal and immunosuppressant activities; inhibits the growth of C. albicans, C. glabrata, and C. krusei (MICs = 0.78-1.56, 0.39-0.78, and 0.78-1.56 µg/ml, respectively); induces expansion of Tregs and decreases the number of Th1 and T17 cells in vitro; reduces IL-6, TNF-α, and IFN-γ production, inflammation, and synovitis in a mouse model of collagen-induced arthritis at 10 mg/kg; suppresses the differentiation of Th2 cells and reduces levels of IL-4, IL-5, IL-13, and IgE and eosinophil lung infiltration in a mouse model of ovalbumin-induced asthma; increases production of Tregs, reduces production of Th1, Th17, and CD8 T cells, and reduces disease severity in a mouse model of EAE |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 14761-66-1 25795-25-9 Cerulomycin anti-fungal immuno-suppressant Candida CD4+ Foxp3+ CD4 Foxp3 TGFβ Smad STAT IFNγ IL6 TNFα IL4 IL5 IL3 interleukin |
Gene, Accession, CAS # | CAS: 21802-37-9 |
Catalog # | 27625-5 |
Price | $1,186.00 |
Order / More Info | Caerulomycin A from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |