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Product Name | S14161 |
Description | A small molecule inhibitor of cyclins D1-D3 expression that inhibits PI3K activity and arrests cells at the G0/G1 phase in a dose-dependent manner (5-10 µM); induces apoptosis in myeloma and leukemia cell lines (IC50s = < 10 µM) and delays tumor growth in mouse models of leukemia |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | inhibitors inhibits inhibitions cells cycles biology cancers cyclins D1 D2 D3 PI3K tumors leukemia CDKs blood cancers D-cyclins S-14161 S 14161 phosphonositide 3-kinase PI3K G0/G1 phases induces inducer apoptosis myeloma leukemia hematopoietic transactivation |
Gene, Accession, CAS # | CAS: 883046-50-2 |
Catalog # | 14187-1 |
Price | $68.00 |
Order / More Info | S14161 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |