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Product Name | Cu-ATSM |
Description | A copper-containing compound with diverse biological activities; inhibits ferroptotic cell death induced by RSL3, erastin, or iron(II) (EC50s = 134, 169, and 171 nM, respectively), as well as RSL3-, erastin-, or iron-induced lipid peroxidation in N27 rat mesencephalic cells at 1 µM; increases SOD1G37R protein levels, metalation, and activity in the spinal cord in the SOD1G37R transgenic mouse model of ALS at 30 mg/kg per day; increases the number of α-motor neurons and reduces oxidatively modified proteins in the spinal cord, as well as increases the latency to fall in the rotarod test in the same ALS mouse model; versions containing positron-emitting copper isotopes have been used in PET imaging applications for selective labeling of hypoxic tissue |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | copper-ATSM|CuII(atsm) |
Gene, Accession, CAS # | CAS: 68341-09-3 |
Catalog # | 17122-5 |
Price | $93.00 |
Order / More Info | Cu-ATSM from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |