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Product Name | XAV939 |
Description | A small molecule inhibitor of tankyrase 1 and 2 (IC50 = 11 and 4 nM, respectively); increases the protein levels of the axin-GSK3β complex and promotes the degradation of β-catenin; inhibits colony formation of APC-deficient colorectal cancer cells at 0.33 µM |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | Wnt cancers β-catenin APC axin GSK3 poly-ADP-ribosylation tankyrases TNKS1 TNKS2 inhibitors inhibition inhibits |
Gene, Accession, CAS # | CAS: 284028-89-3 |
Catalog # | 13596-25 |
Price | $143.00 |
Order / More Info | XAV939 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |