(±)-Synephrine (hydrochloride) from CAYMAN CHEMICAL COMPANY
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| Product Name | (±)-Synephrine (hydrochloride) |
| Description | An alkaloid with vasoconstrictor and metabolic activities; binds to α1A-, α2A-, and α2C-adrenergic receptors (ARs; Kis = 78, 36.7, and 24.4 µM, respectively); an agonist of α1A-ARs in HEK293 cells (EC50 = 4 µM) but not in CHO cells expressing α2A- or α2C-AR; acts as an antagonist of α1A-, α2A-, and α2C-ARs, inhibiting L-phenylephrine-induced activation of α1A-AR in HEK293 cells and medetomidine-induced activation of α2A- and α2C-ARs in CHO cells (IC50s = 12.8, 26, and 27.3 µM, respectively); induces contractions in isolated rabbit aortic rings (EC50 = 6.2 µg/ml) and increases ligation-induced mean arterial pressure in rats at 2 mg/kg per day; induces lipolysis in isolated rat and human adipocytes when used at 100 and 1,000 µg/ml; increases phosphorylation of Akt and AMPK and translocation of Glut4 to the plasma membrane at 50 µM; increases insulin-induced glucose consumption in L6 muscle cells when used at 25-200 µM |
| Size | 25 g |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 614-35-7 582-84-3 860222-98-6 Sympatol Oxedrine p-synephrine α-1A 2A 2C α1AARs HEK-293 α2AARs α2CARs Glut-4 α2AR |
| Gene, Accession, CAS # | CAS: 5985-28-4 |
| Catalog # | 28398-25 |
| Price | $152.00 |
| Order / More Info | (±)-Synephrine (hydrochloride) from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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