EP4 Antagonist 14 from CAYMAN CHEMICAL COMPANY
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| Product Name | EP4 Antagonist 14 |
| Description | An EP4 antagonist (IC50 = 1.1 nM in a reporter assay); inhibits PGE2-induced β-arrestin recruitment in the same cells (IC50 = 0.9 nM); decreases PGE2-induced expression of mRNA encoding Il4, Mrc1, Chil3, Cxcl1, Trem2, and Arg1 in RAW 264.7 macrophages at 10 µM; inhibits tumor growth and increases infiltration of CD8+ T cells into tumors in combination with an anti-PD-1 antibody in a CT26 murine colon cancer model at 30 mg/kg per day |
| Size | 1 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | PGE2 Receptor 4 Antagonist 14|Prostaglandin E2 Receptor 4 Antagonist 14 |
| Gene, Accession, CAS # | n/a |
| Catalog # | 38427-1 |
| Price | $67.00 |
| Order / More Info | EP4 Antagonist 14 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY