GSK8612 from CAYMAN CHEMICAL COMPANY
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| Product Name | GSK8612 |
| Description | A TBK1 inhibitor (IC50 = 158 nM); selective for TBK1 over a panel of 285 kinases; inhibits IFN-α release in poly(I:C)-stimulated isolated human PBMCs (IC50 = 794 nM); inhibits IFN-β secretion in THP-1 cells stimulated with dsDNA-containing baculovirus or cGAMP (IC50s = 1,258 and 501 nM, respectively); reduces tumor volume and increases the number of tumor-infiltrating CD8+ T cells in immunocompetent, but not immunodeficient, mice in a model of carbon tetrachloride-induced HCC at 5 mg/kg |
| Size | 50 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | GSK 8612 THP1 |
| Gene, Accession, CAS # | CAS: 2361659-62-1 |
| Catalog # | 28813-50 |
| Price | $398.00 |
| Order / More Info | GSK8612 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY