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Product Name | MPT0B014 |
Description | A tubulin polymerization inhibitor; inhibits proliferation of A549, H1299, and H226 human NSCLC cells (IC50s = 0.041, 0.046, and 0.041 µM, respectively), as well as adriamycin-resistant NCI/ADR cells that overexpress P-glycoprotein (IC50 = ~0.03 µM); induces cell cycle arrest at the G2/M phase and apoptosis in A549 cells at 0.3 µM; reduces tumor growth in an A549 mouse xenograft model when administered in combination with erlotinib |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | MPT-0B014 MPT0-B014 A-549 H-1299 226 |
Gene, Accession, CAS # | CAS: 1215208-59-5 |
Catalog # | 21718-10 |
Price | $189.00 |
Order / More Info | MPT0B014 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |