ERB 041 from CAYMAN CHEMICAL COMPANY
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| Product Name | ERB 041 |
| Description | An ERβ agonist (IC50s = 5.4, 3.1, and 3.7 nM for the human, rat, and mouse receptors, respectively); selective for ERβ over ERα (IC50s = 1,200, 620, and 750 nM for the human, rat, and mouse ERα, respectively); induces IGFBP4 mRNA expression in Saos-2 cells expressing human ERβ (EC50 = 20 nM); inhibits chronic diarrhea and reduces colonic ulceration, inflammation, and fibrosis in the HLA-B27 transgenic rat model of inflammatory bowel disease at 0.1 and 0.3 mg/kg; reduces joint swelling in a rat model of adjuvant-induced arthritis at 1 mg/kg; reduces lesion formation in a mouse model of endometriosis at 10 mg/kg |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | ERB041 Prinaberel ER-β α IGFBP-4 Saos2 HLAB27 |
| Gene, Accession, CAS # | CAS: 524684-52-4 |
| Catalog # | 28737-5 |
| Price | $87.00 |
| Order / More Info | ERB 041 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY