ASP9521 from CAYMAN CHEMICAL COMPANY
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| Product Name | ASP9521 |
| Description | An inhibitor of 17β-HSD5/AKR1C3 (IC50 = 120 nM); selective for 17β-HSD5/AKR1C3 over AKR1C2 (IC50 = 20 µM); inhibits conversion of androstenedione into testosterone by 17β-HSD5/AKR1C3 (IC50s = 11 and 49 nM for human and cynomolgus monkey enzymes, respectively); inhibits androstenedione-dependent PSA production in and proliferation of LNCaP cells expressing 17β-HSD5/AKR1C3; inhibits androstenedione-induced intratumor testosterone production in a CWR22R prostate cancer mouse xenograft model at 3 and 10 mg/kg |
| Size | 25 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | ASP-9521 hydroxy-steroid 5-aldo 1-C3 1C-3 HSD-5 ARK-1C3 ARK1C-3 ARK-1C2 ARK1C-2 17-βHSD5 ASP-9521 intra-tumor CWR-22R CWR22-R |
| Gene, Accession, CAS # | CAS: 1126084-37-4 |
| Catalog # | 27308-25 |
| Price | $166.00 |
| Order / More Info | ASP9521 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY