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Product Name | ASK1 Inhibitor 10 |
Description | An orally bioavailable inhibitor of ASK1 (IC50 = 14 nM); selective for ASK1 over ASK2 (IC50 = 510 nM) as well as MEKK1, TAK-1, IKKβ, ERK1, JNK1, p38α, GSK3β, PKCθ, and B-RAF (IC50s = >10,000 nM for all); inhibits streptozotocin-induced increases in JNK and p38 phosphorylation in INS-1 pancreatic β cells in a concentration-dependent manner |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 1005775-55-2 ASK MEKK TAK1 IKK ERK JNK p38-α p-38α 38 GSK3 GSK-3 3β PKC-θ BRAF INS1 |
Gene, Accession, CAS # | CAS: 1005775-56-3 |
Catalog # | 28512-10 |
Price | $214.00 |
Order / More Info | ASK1 Inhibitor 10 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |