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Product Name | ER-819762 |
Description | An antagonist of EP4 (IC50 = 70 nM); selective for EP4 over EP1, EP2, and EP3 in a cAMP reporter assay at 10 µM; reduces differentiation of mouse helper T cells at 0.1 to 10 nM and decreases IL-23 secretion by mouse dendritic cells at 0.04 to 5 nM; reduces MDV levels in CEFs at 1 µM; prevents and reverses paw swelling, edema, and inflammation at 30 and 100 mg/kg in a mouse model of rheumatoid arthritis induced by GPI |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | ER819762 IL23 |
Gene, Accession, CAS # | CAS: 1155773-15-1 |
Catalog # | 10531-5 |
Price | $345.00 |
Order / More Info | ER-819762 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |