VS-5584 from CAYMAN CHEMICAL COMPANY

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Product NameVS-5584
DescriptionA purine analog that inhibits mTOR (IC50 = 37 nM) and PI3K (IC50s = 16, 68, 25, and 42 nM for the α, β, γ, and δ isoforms, respectively); demonstrates broad anti-proliferative sensitivity leading to tumor growth inhibition in human tumor models
Size10 mg
Concentrationn/a
Applicationsn/a
Other Namesinhibitor mTOR PI3K antiproliferation antitumor cancer inhibit biochemical intracellular signaling kinase m-TOR anti-proliferation anti-tumor phosphatidylinositol 3-kinase Akt/PKB Akt PKB PI3K/mTOR mammalian target rapamycin gene expression cell differentiation apoptosis VS5584 purine analog α β γ δ isoform PI3Kα PI3Kβ PI3Kγ PI3Kδ phosphorylation substrate downstream board sensitivity tumor growth human model
Gene, Accession, CAS #CAS: 1246560-33-7
Catalog #16294-10
Price$230.00
Order / More InfoVS-5584 from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
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http://www.caymanchem.com

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