Edit |   |
---|---|
Product Name | Pirenzepine (hydrochloride) |
Description | A muscarinic M1 receptor antagonist (Ki = 11.48 nM); selective for M1 over M2, M3, and M4 receptors (Kis = 602.56, 151.36, and 199.53 nM, respectively); inhibits ascending reflex contraction of the circular smooth muscle in isolated guinea pig ileal segments induced by intraluminal balloon inflation (IC50 = 501.19 nM); inhibits methacholine-induced increases in ileal pressure in guinea pigs (ID50 = 724.44 nmol/kg); inhibits oxotremorine-induced gastric ulcer, gastric acid secretion, and salivation in rats (ED50 = 13, 37.5, and 620 µg/kg i.v., respectively); prevents FDM in a chick model of experimental myopia |
Size | 1 g |
Concentration | n/a |
Applications | n/a |
Other Names | Gastrozepin |
Gene, Accession, CAS # | CAS: 29868-97-1 |
Catalog # | 29527-1 |
Price | $152 |
Order / More Info | Pirenzepine (hydrochloride) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |