Tankyrase-IN-2 from CAYMAN CHEMICAL COMPANY
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| Product Name | Tankyrase-IN-2 |
| Description | A TNKS1 and TNSK2 inhibitor (IC50s = 7 and 9.2 nM, respectively); selective for TNKS1 and TNKS2 over a panel of 10 additional PARP enzymes (IC50s = 710->10,000 nM for the human enzymes); increases accumulation of Axin2 and TNKS in DLD-1 colorectal cancer cells (EC50s = 319 and 320 nM, respectively); increases tumor Akin2 and TNKS accumulation, as well as decreases tumor β-catenin levels, in a DLD-1 mouse xenograft model at 10, 30, and 90 mg/kg |
| Size | 500 µg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | TNKS-1 2 PARP Axin-2 DLD1 |
| Gene, Accession, CAS # | CAS: 1588870-36-3 |
| Catalog # | 29808-500 |
| Price | $112.00 |
| Order / More Info | Tankyrase-IN-2 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY