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Product Name | BGJ398 (phosphate) |
Description | A pan FGFR inhibitor (IC50s = 0.9, 1.4, and 1 nM for FGFR1, FGFR2, and FGFR3, respectively); suppresses proliferation of cancer cells with wild-type FGFR3 overexpression (IC50s = 5, 30, 32, and 15 nM, for RT112, RT4, SW780, and JMSU1 cells, respectively); inhibited tumor growth in an RT112 bladder cancer xenograft mouse model overexpressing wild-type FGFR3 at 10-30 mg/kg |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | Infigratinib (phosphate)|NVP-BGJ398 (phosphate) |
Gene, Accession, CAS # | CAS: 1310746-10-1 |
Catalog # | 39292-10 |
Price | $138.00 |
Order / More Info | BGJ398 (phosphate) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |