TC 2559 (fumarate) from CAYMAN CHEMICAL COMPANY
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| Product Name | TC 2559 (fumarate) |
| Description | A partial agonist for α4β2 subunit-containing nAChRs (EC50 = 0.18 µM); selective for α4β2 over α2β4, α4β4, α3β4, α3β2, and α7 subunit-containing nAChRs (EC50s = 14, 12.5, >30, >100, and >100 µM, respectively); increases dopamine cell firing in the rat VTA in vitro; enhances inhibitory synaptic transmission in dorsal horn neurons via α4β2 subunit-containing nAChRs; reduces formalin-induced paw-licking time in mice at 3 and 10 mg/kg; reverses scopolamine-induced cognitive deficits in rats in a step-through passive avoidance test at 3 and 6 µmol/kg |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 212332-35-9 189274-78-0 TC2559 HEK-293 α-7 2 4 3 β TC-2557 TC2557 |
| Gene, Accession, CAS # | CAS: 212332-35-9 |
| Catalog # | 25600-5 |
| Price | $139.00 |
| Order / More Info | TC 2559 (fumarate) from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY