S 14506 from CAYMAN CHEMICAL COMPANY
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| Product Name | S 14506 |
| Description | A 5-HT1A receptor agonist; selectively binds 5-HT1A over 5-HT1B, 5-HT1C, 5-HT2, and 5-HT3 receptors (Kis = 0.98, 281.8, 31.6, 229, and >1,000 nM, respectively) but also binds the dopamine D2 receptor (Ki = 4.57 nM) in radioligand binding assays; stimulates GTPase activity in HEK293 cell membranes expressing 5-HT1A-Gi1α or 5-HT1A-Go1α fusion proteins; reduces immobility time in the forced swim test in rats (MED = 0.01 mg/kg); increases punished responding in a pigeon conflict procedure from 0.0025-0.63 mg/kg |
| Size | 10 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 5HT1A HT-1A 5HT 1B 1C HEK-293 D-2 S14506 |
| Gene, Accession, CAS # | CAS: 135722-25-7 |
| Catalog # | 32838-10 |
| Price | $184.00 |
| Order / More Info | S 14506 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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