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Product Name | CC-90009 |
Description | A modulator of cereblon; binds to cereblon and enhances the protein-protein interaction between cereblon and GSPT1 to induce ubiquitination and proteasomal degradation of GSPT1; inhibits the growth of U937 cells from 0.01-10 µM; inhibits cell growth in a panel of AML cells; induces intratumor GSPT1 degradation in AML mouse xenograft models and decreases leukemic engraftment of 35 patient-derived AML samples in NOD.SCID mice |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | CC90009 |
Gene, Accession, CAS # | CAS: 1860875-51-9 |
Catalog # | 33692-10 |
Price | $231.00 |
Order / More Info | CC-90009 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |