Edit |   |
---|---|
Product Name | NQ301 |
Description | A naphthoquinone with diverse biological activities; inhibits U-46619-induced rabbit platelet aggregation in vitro (IC50 = 0.58 µM); inhibits the conversion of arachidonic acid to thromboxane B2 in rabbit platelets; inhibits human platelet aggregation induced by ADP, collagen, epinephrine, and A23187 in vitro (IC50s = 3.21, 15.69, 8.44, and 44.2 µM, respectively); increases tail bleeding time and exhibits a protective effect against pulmonary thrombosis in mice at 50 and 100 mg/kg; inhibits CD45 (IC50 = 0.29 µM); inhibits ovalbumin-induced footpad swelling in a mouse model of delayed-type hypersensitivity at 3 mg/kg; is active against C. albicans, A. niger, B. subtilis, S. aureus, E. coli, and P. aeruginosa (MICs = 12.5-50 µg/ml) |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | NQ-301 CD45 CD-45 A-2 B platelet thrombotic antiinflammatory microbial U46619 A-23187 Candida Aspergillus Bacillus Staphylococcus Escherichia Pseudomonas |
Gene, Accession, CAS # | CAS: 130089-98-4 |
Catalog # | 21958-1 |
Price | $32.00 |
Order / More Info | NQ301 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |