Edit |   |
---|---|
Product Name | MRTX-1133 |
Description | An inhibitor of K-RasG12D; selectively reduces ERK phosphorylation in AsPC-1 cells expressing mutant K-RasG12D (IC50 = 10.8 nM) over MiaPaCa-2 and SW620 cells expressing mutant K-RasG12C or K-RasG12V (IC50s = 456 and 4,400 nM, respectively) and MCF-7 cells expressing wild-type K-Ras in which ERK phosphorylation was not reduced |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | MRTX1133 KRAS AsPC1 SW-620 MiaPaCa2 AsPC1 MCF7 |
Gene, Accession, CAS # | CAS: 2621928-55-8 |
Catalog # | 36413-1 |
Price | $81.00 |
Order / More Info | MRTX-1133 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |