Nitecapone from CAYMAN CHEMICAL COMPANY

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Product NameNitecapone
DescriptionAn S-COMT inhibitor (IC50 = 300 nM in rat liver); is selective for S-COMT over tyrosine hydroxylase, dopamine-β-hydroxylase, DOPA decarboxylase, MAO-A, and MAO-B (IC50s = >1 µM for all); inhibits liver, duodenal, and brain S-COMT (ID50s = 5, 5, and 25 mg/kg, respectively); reduces 3-OMD formation and increases serum and brain L-DOPA, dopamine, and DOPAC levels when administered in combination with L-DOPA and carbidopa from 3-30 mg/kg; reduces mechanical and cold allodynia in a rat model of spinal nerve ligation-induced neuropathy at 30 mg/kg
Size5 mg
Concentrationn/a
Applicationsn/a
Other NamesOR-462
Gene, Accession, CAS #CAS: 116313-94-1
Catalog #18656-5
Price$73.00
Order / More InfoNitecapone from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com

http://www.caymanchem.com

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