LOXO-195 from CAYMAN CHEMICAL COMPANY
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| Product Name | LOXO-195 |
| Description | An inhibitor of TrkA and TrkC (IC50s = 0.6 and G595R, TrkAG667C, TrkCG623R, and TrkCG696A (IC50s = 2, 9.8, 2.3, and 50 = 1.9 nM); selectively inhibits proliferation of Trk fusion-positive K12, CUTO-3, and MO-91 cell lines (IC50s = ≤5 nM) over Trk fusion-negative cell lines; reduces tumor growth in TrkA-dependent KM12, as well as NIH 3T3 ΔTrkA, ΔTrkA + TrkAG595R, and ΔTrkA + TrkAG667C mouse xenograft models at ≥30 mg/kg |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | Selitrectinib |
| Gene, Accession, CAS # | CAS: 2097002-61-2 |
| Catalog # | 27062-5 |
| Price | $684.00 |
| Order / More Info | LOXO-195 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY