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Product Name | MHY908 |
Description | A PPARα and PPARγ dual agonist; increases transcriptional activity of PPARα and PPARγ in a luciferase reporter assay in AC2F rat liver cells at 5 µM; reduces serum glucose, triglyceride, and insulin levels and improves hepatic steatosis in db/db mice and 20-month-old rats at 3mg/kg; reduces peroxynitrite and COX-2 levels, ROS production, and Akt phosphorylation in 20-month-old rat kidney at 3 mg/kg; inhibits mushroom tyrosinase (IC50 = 8.19 µM); inhibits increases in melanin content in α-melanocyte stimulating hormone-induced B16/F10 murine melanoma cells at 10 µM. |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | peroxisome proliferator activated receptor PPAR PPARα PPAR-α PPARa PPAR-a PPARγ PPAR-γ PPARg PPAR-g MHY-908 NASH non-alcoholic nonalcoholic steatohepatitis NAFLD nonalcoholic fatty liver disease |
Gene, Accession, CAS # | CAS: 1393371-39-5 |
Catalog # | 18293-10 |
Price | $508.00 |
Order / More Info | MHY908 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |