Edit |   |
---|---|
Product Name | Ensifentrine |
Description | A PDE3 inhibitor (IC50 = 0.4 nM); selective for PDE3 over PDE4 (IC50 = 1,479 nM); reduces the phytohemagglutinin-induced proliferation of isolated human monocytes; inhibits LPS-induced increases of TNF-α protein levels in isolated human monocytes (IC50 = 520 nM); increases cAMP levels in isolated human neutrophils at 10 µM; inhibits electric field stimulation-induced contractile responses in isolated guinea pig trachea in a concentration-dependent manner; intranasal administration inhibits histamine-induced bronchoconstriction and tracheal edema in guinea pigs at 25% w/w |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | RPL 554|VMX 554 |
Gene, Accession, CAS # | CAS: 1884461-72-6 |
Catalog # | 38761-1 |
Price | $30.00 |
Order / More Info | Ensifentrine from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |