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Product Name | MSAB |
Description | An inhibitor of Wnt/β-catenin signaling; selectively inhibits the proliferation of Wnt-dependent cancer cells over non-cancerous cells and Wnt-independent cancer cells at 2-10 µM; decreases the expression of the Wnt target genes AXIN2, MYC, CCND1, and BMP4 in a concentration-dependent manner in HCT116 cells; reduces tumor growth and increases intratumoral apoptosis in Wnt-dependent HCT116, HT115, and H23 mouse xenograft models at 10 and 20 mg/kg |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | HCT 116 noncancerous HEK 293T AXIN 2 CCND 1 BMP 4 HT 115 H 23 methyl 3-[[(4-methylphenyl)sulfonyl]amino]benzoate |
Gene, Accession, CAS # | CAS: 173436-66-3 |
Catalog # | 36497-25 |
Price | $60.00 |
Order / More Info | MSAB from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |