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Product Name | KB-R7943 (mesylate) |
Description | A selective inhibitor of the reverse mode of NCX1 (IC50 = 1.2-2.4 µM) that prevents intracellular sodium-dependent calcium uptake in whole cells; exhibits neuroprotection from glutamate-induced excitotoxicity; inhibits TRPC channels involved in calcium-dependent signal transduction |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 182004-64-4 inhibitors inhibits inhibitions NCX1 Na+/Ca2+ sodium/calcium Na+ Ca2+ exchangers sodium calcium neuroprotection TRPC signals transduction mesylate KBR7943 KB R7943 KB-R 7943 R reverse NCX isothiourea derivatives selective selectively sodium-dependent dependent neurons NMDA receptors complex I 1 one mitochondria mitochondrial respiratory chains transient potential canonical channels cardiology ions pumps blockers biology neurosciences |
Gene, Accession, CAS # | CAS: 182004-65-5 |
Catalog # | 16352-10 |
Price | $77.00 |
Order / More Info | KB-R7943 (mesylate) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |