Saikosaponin A from CAYMAN CHEMICAL COMPANY
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| Product Name | Saikosaponin A |
| Description | A triterpenoid saponin with diverse biological activities; reduces expression of TNF-α, IL-6, and IL-1β in LPS-stimulated primary mouse macrophages; increases the survival rate in mice with LPS-induced lethal endotoxemia; reduces weight loss, brain edema, blood-brain barrier disruption, and cortex IL-6 and TNF-α protein levels in the ipsilateral cortex in a rat model of traumatic brain injury at 20 mg/kg; reduces the number of nasal rubs and levels of serum TNF-α in an ovalbumin-sensitized allergic rhinitis mouse model in vivo at 8 mg/kg; reduces duration and frequency of epileptiform discharges in rat hippocampal CA1 neurons in a 4-AP seizure model; decreases viability in six HCC, H358 lung and MCF-7 breast cancer, as well as Jurkat and K582 leukemia cell lines at 20 µM; prolongs tumor growth inhibition in LoVo and SW480 HCC mouse xenograft models in vivo at 2 mg/kg |
| Size | 1 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | Salikosaponin Oleanane SsA TNFα IL6 IL1β 4AP C-A1 H-358 MCF7 K-582 SW-480 antiinflammatory anti-allergic convulsive proliferative viral |
| Gene, Accession, CAS # | CAS: 20736-09-8 |
| Catalog # | 25026-1 |
| Price | $37.00 |
| Order / More Info | Saikosaponin A from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY