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Product Name | MRX-2843 |
Description | A Mer and FLT3 inhibitor (IC50s = 1.3 and 1 nM, respectively); inhibits Axl and Tyro3 (IC50s = 15 and 17 nM, respectively); inhibits Mer phosphorylation in MOLM-14 and MV4-11 AML cells from 10-300 nM; reduces clonal expansion of Kasumi-1 AML cells (IC50 = 143.5 nM); increases survival in a NOMO-1 and MOLM-14 AML mouse xenograft models at 65 and 50 mg/kg, respectively |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | MRX2843 MOLM14 MV411 1AML NOMO1 Tyro-3 UNC-2371A UNC2371A UNC-2371-A |
Gene, Accession, CAS # | CAS: 1429882-07-4 |
Catalog # | 27923-1 |
Price | $49.00 |
Order / More Info | MRX-2843 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |