Romidepsin from CAYMAN CHEMICAL COMPANY
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| Product Name | Romidepsin |
| Description | A natural bicyclic depsipeptide that selectively inhibits class I HDACs (IC50s = 53, 39, 53, and 26 nM, for HDAC1, 2, 3, and 8, respectively) over HDAC4, 6, 7, and 9 (IC50s = 470, 330, 3,200, and 12,000 nM, respectively); has anti-cancer activities, particularly against certain T cell lymphomas; increases mRNA expression, histone acetylation, and the levels of proteins involved in NMDA receptor function in the brain of Shank3-deficient mice; rescues autism-like deficits in Shank3-deficient mice for at least three weeks following a dose of 0.25 mg/kg per day for three days |
| Size | 500 µg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | FK228|FR901228|NSC 630176 |
| Gene, Accession, CAS # | CAS: 128517-07-7 |
| Catalog # | 17130-500 |
| Price | $110 |
| Order / More Info | Romidepsin from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY