5α,6β-Dihydroxycholestanol from CAYMAN CHEMICAL COMPANY
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| Product Name | 5α,6β-Dihydroxycholestanol |
| Description | An oxysterol metabolite of cholesterol; inhibits NMDA-mediated calcium influx in HEK293 cells expressing NR1/NR2B NMDA receptors; binds to Nav channels and decreases action potentials in hippocampal neurons in vitro at 10 µM; increases survival of spinal cord motoneurons, cortical neurons, and cerebellar granule neurons in vitro at 5-15 µM; neuroprotective in a rat model of cerebral ischemia at 12 mg/kg ; increases latency to seizure onset and reduces severity of PTZ-induced seizures in rats; has been used as a replacement for cholesterol in the study of cholesterol binding proteins |
| Size | 25 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 5α,6β-di-OHC|Cholestanetriol|NSC 124751|NSC 18178 |
| Gene, Accession, CAS # | CAS: 1253-84-5 |
| Catalog # | 25538-25 |
| Price | $356.00 |
| Order / More Info | 5α,6β-Dihydroxycholestanol from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY