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Product Name | Quarfloxin |
Description | An inhibitor of RNA polymerase I-mediated transcription; binds to G-quadruplex DNA and inhibits the interaction between ribosomal DNA G-quadruplexes and nucleolin; induces nucleolin mislocalization from the nucleoli to the nucleoplasm in A549 cells at 10 µM; induces apoptosis in A549 and HL-60 cells at 5 µM; reduces tumor growth in MDA-MB-231 and MiaPaCa-2 mouse xenograft models at 5 mg/kg |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | CX-3543|Itarnafloxin|Quarfloxacin |
Gene, Accession, CAS # | CAS: 865311-47-3 |
Catalog # | 36552-5 |
Price | $272 |
Order / More Info | Quarfloxin from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |