Sauchinone from CAYMAN CHEMICAL COMPANY
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| Product Name | Sauchinone |
| Description | A lignan with diverse biological activities; inhibits LPS-induced expression of the genes encoding iNOS, TNF-α, and COX-2 (IC50s = ≤10 µM for all), as well as LPS-induced activation of NF-κB and nuclear translocation of NF-κB p65 in RAW 264.7 cells; reduces hydrogen peroxide-induced increases in Hsp70 levels and cell death in C2C12 mouse skeletal muscle myoblasts; reduces hepatic formation of TBARS, plasma levels of ALT, and hepatocyte cell death in a mouse model of iron overload-induced liver injury at 10 and 30 mg/kg; reduces infarct size and heart levels of phosphorylated p38 MAPK and JNK in a rat model of myocardial ischemia-reperfusion injury |
| Size | 10 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | antiinflammatory lignan lignin antiangiogenic antinociceptive cardioprotective HO-1 HO1 Schisandra NFκB NF-kB NFkB Schisandra TNFα COX2 NFκB p 65 Hsp |
| Gene, Accession, CAS # | CAS: 177931-17-8 |
| Catalog # | 19577-10 |
| Price | $199.00 |
| Order / More Info | Sauchinone from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY