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Product Name | KD 025 |
Description | A ROCK2 inhibitor (IC50 = 0.105 µM); selective for ROCK2 over ROCK1 (IC50 = 24 µM); decreases the expression of CTGF and induces remodeling of the actin cytoskeleton in isolated human ileal fibrotic smooth muscle cells at 10 µM; inhibits heat-killed C. albicans- or S. epidermidis-induced production of IL-17 in isolated human PBMCs at 1.25-10 µM; reduces infarct volume in a mouse model of cerebral ischemia induced by transient MCAO at 100 and 200 mg/kg; decreases disease severity in a mouse model of sclerodermatous chronic GVHD at 150 mg/kg |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | Belumosudil|SLx-2119 |
Gene, Accession, CAS # | CAS: 911417-87-3 |
Catalog # | 17055-50 |
Price | $236.00 |
Order / More Info | KD 025 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |