C527 from CAYMAN CHEMICAL COMPANY
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| Product Name | C527 |
| Description | An inhibitor of the USP1/UAF complex; inhibits USP1/UAF deubiquitinase activity (IC50 = 0.88 µM); inhibits USP5, UCL-H3, and USP12/46 but not UCL-H1 activity (IC50s = 1.65, 2.18, 5.97, and >10 µM, respectively); inhibits homologous recombination repair, cell proliferation, and sensitizes HeLa cells to the DNA crosslinker mitomycin C; inhibits proliferation of PC3 and LNCap prostate cancer cells (IC50s = 0.24 and 0.03 µM, respectively, after 72 hours) |
| Size | 10 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | C-527 USP-5 UCLH3 1 USP-12/46 PC-3 D-2 |
| Gene, Accession, CAS # | CAS: 192718-06-2 |
| Catalog # | 21771-10 |
| Price | $143.00 |
| Order / More Info | C527 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY