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Product Name | MI-2 |
Description | An inhibitor of menin-MLL fusion protein interactions (IC50 = 446 nM); binds to menin (Kd = 158 nM) and inhibits the menin-MLL-AF9 interaction in HEK293 cells; inhibits growth of mouse BMCs expressing the Hoxa9 transformation-dependent MLL-AF9 (GI50 = 5 µM); inhibits the growth of MV4, KOPN-8, ML-2, and MonoMac6 MLL cells expressing MLL fusion proteins (GI50s = 9.5, 7.2, 8.7, and 18 µM, respectively) |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | MI2 MLLAF9 AF 9 HEK 293 Hoxa MV 4 KOPN8 Mono Mac6 Mac 6 |
Gene, Accession, CAS # | CAS: 1271738-62-5 |
Catalog # | 29218-50 |
Price | $625.00 |
Order / More Info | MI-2 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |