TC LPA5 4 from CAYMAN CHEMICAL COMPANY
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| Product Name | TC LPA5 4 |
| Description | An LPA5 antagonist (IC50 = 0.8 µM in McA-RH7777 cells expressing the human receptor); selectively inhibits the aggregation of washed isolated human platelets induced by 1-palmitoyl LPA over collagen or TRAP (IC50s = 0.8, >10, and >10 µM, respectively); inhibits NSD2 (IC50 = 8.5 µM) and 29 other methyltransferases (IC50s = 0.33-71 µM); reduces tumor volume in a CGTH-W-3 thyroid cancer mouse xenograft model at 10 mg/kg; prevents brain tissue loss and neurological deficits, as well as increases survival, neurogenesis in the subventricular zone, and angiogenesis in the penumbra, in a mouse model of transient MCAO-induced ischemic stroke at 10 mg/kg, i.p. |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | TC Lysophosphatidic Acid Receptor 5 4 |
| Gene, Accession, CAS # | CAS: 1393814-38-4 |
| Catalog # | 17719-5 |
| Price | $149.00 |
| Order / More Info | TC LPA5 4 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY