KB-0742 (hydrochloride) from CAYMAN CHEMICAL COMPANY
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| Product Name | KB-0742 (hydrochloride) |
| Description | A Cdk9 inhibitor (IC50 = 6 nM); selective for Cdk9 over Cdk1-8 (IC50s = 397->10,000 nM) and Cdk12-19 (IC50s = 372->10,000 nM); induces cell cycle arrest at the G1 phase and apoptosis in BT-20, BT-549, MDA-MB-231, MT-3, and Hs 578T TNBC cells from 0.64-7.73 µM; reduces tumor volume in the MYC-amplified CTG-0437 PDX mouse model of TNBC at 60 mg/kg |
| Size | 25 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 2416873-83-9 2416874-75-2 KB0742 Cdk Cdk18 Cdk1219 1219 12 19 G-1 BT20 BT549 MDAMB MB231 MDAMB231 MT3 CTG0437 |
| Gene, Accession, CAS # | n/a |
| Catalog # | 39772-25 |
| Price | $380.00 |
| Order / More Info | KB-0742 (hydrochloride) from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY