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Product Name | MS023 (hydrochloride) |
Description | An inhibitor of type I PRMTs (IC50s = 30, 119, 83, 4, and 5 nM for PRMT1, -3, -4, -6, and -8, respectively); selective for these type I PRMTs over PRMT5, -7, and -9, as well as a panel of 25 PKMTs and DNMTs at 10 µM; inhibits methylation of H4R3 in MCF-7 cells and H3R2 in HEK293 cells (IC50s = 9 and 56 nM, respectively); inhibits methylation of the SARS-CoV-2 nucleocapsid protein and the replication of SARS-CoV-2 in Vero E6 cells at 20 µM; reduces tumor growth in a Huh7 mouse xenograft model at 160 mg/kg |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 1831110-54-3 MS-023 MS-23 MS23 PRMT3 PRMT4 PRMT6 PRMT8 PRMT7 PRMT9 MCF7 HEK-293 COVID19 SARSCoV2 SARS-CoV2 SARSCoV VeroE6 Huh-7 |
Gene, Accession, CAS # | CAS: 2108631-19-0 |
Catalog # | 18361-25 |
Price | $957.00 |
Order / More Info | MS023 (hydrochloride) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |