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Product Name | Rec 15/2615 (hydrochloride) |
Description | An α1B-AR antagonist (Ki = 0.45 nM for the recombinant human receptor); selectively inhibits α1B-ARs over α1A-, α1D-, and α1L-ARs (Kis = 7.59, 10.23, and 49 nM, respectively); inhibits norepinephrine-induced contractions of isolated rabbit prostate and urethral strips (Kis = 100 and 316.2 nM, respectively), and reduces norepinephrine-induced contractions of chloroethylclonidine-precontracted isolated rabbit aortic rings (Ki = 50 nM); decreases diastolic blood pressure (ED25 = 183 µg/kg, i.v.) and increases intracavernous pressure in anesthetized dogs when administered intracavernously at 30-1,000 µg/kg |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | SB 216469 |
Gene, Accession, CAS # | CAS: 1782573-48-1 |
Catalog # | 27677-25 |
Price | $479 |
Order / More Info | Rec 15/2615 (hydrochloride) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |