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Product Name | Trequinsin (hydrochloride) |
Description | A cAMP-dependent PDE3 inhibitor (IC50s = 0.04 and 0.03 nM for PDE3A and PDE3B, respectively in T84 cell lysates); stimulates cAMP accumulation (10 µM) and increases membrane capacitance in rat juxtaglomerular cells; competitively inhibits multidrug resistant protein 5-mediated export of cGMP from Chinese hamster lung fibroblasts (Ki = 240 nM); reduces collagen-induced platelet aggregation in rabbits (3 µg/kg per minute); reduces collagen-induced decreases in mean arterial blood pressure alone or in combination with prostacyclin |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 79855-88-2 HL725 T-84 PDE-3A 3B 3 HL-725 PDE3 MDR5 MDR-5 |
Gene, Accession, CAS # | CAS: 78416-81-6 |
Catalog # | 17217-1 |
Price | $44.00 |
Order / More Info | Trequinsin (hydrochloride) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |