NMS-1286937 from CAYMAN CHEMICAL COMPANY
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| Product Name | NMS-1286937 |
| Description | An inhibitor of Plk1 (IC50 = 2 nM); selective for Plk1 over Plk2 and Plk3 (IC50s = >10,000 nM for both); inhibits proliferation of A2780 cells (IC50 = 42 nM); halts the cell cycle at the G2/M phase in A2780 cells at 20-200 nmol/L and induces apoptosis; reduces tumor growth in an HCT116 mouse xenograft model at 60 mg/kg once per day; induces tumor regression in an HT-29 mouse xenograft model at 45 mg/kg in combination with CPT11 |
| Size | 25 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | NMS-P937|Onvansertib|PCM-075 |
| Gene, Accession, CAS # | CAS: 1034616-18-6 |
| Catalog # | 28762-25 |
| Price | $381.00 |
| Order / More Info | NMS-1286937 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
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http://www.caymanchem.com
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